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We engineer our antibodies for top down impact

By targeting activated immune cells in both the periphery and affected tissues, we modulate the critical pathways that regulate autoimmunity and inflammation.

Dysregulated immune responses fuel a wide range of autoimmune and inflammatory diseases across gastroenterology, rheumatology, dermatology and respiratory therapeutic areas. These large, underserved patient populations often receive treatments that fall short, and our science aims to make a meaningful difference.

image of Matthew in the lab

Matthew working in the First Tracks Lab

Publications and relevant literature

ANB033

Poster Presentation
June, 2023
Federation of Clinical Immunology Societies (FOCIS) Annual Meeting

Discovery of a Novel High Affinity Anti-Human CD122 Antagonist Monoclonal Antibody (ANB033) that Abrogates IL-2 and IL-15 Signaling for the Treatment of T Cell-Mediated Inflammatory and Autoimmune Diseases

Hare et al., 2023

Rosnilimab